成人肺结核精准免疫防治的新方案研究,2018-01 ~ 2021-9,科技部传染病防治国家科技重大专项子课题
敲除抑制自噬基因增强卡介苗介导的自噬对结核病的预防和机制,2018-01 ~ 2021-12,国家自然科学基金委面上项目
IL-10调节卡介苗初免-加强策略预防结核分枝杆菌原发感染的效应和机制,2020-01 ~ 2023-12,国家自然科学基金委面上项目
新冠肺炎基因工程重组蛋白亚单位疫苗的研制,2020-07-2022-12,武汉市科技局应用基础前沿项目
奖励和荣誉:
2020年度,《医学微生物学》线上线下混合式一流课程,教育部国家级首批一流本科课程负责人
2020年度,《医学微生物学》慕课,湖北省一流本科课程负责人
2016年度,“优秀教师班主任”称号,bat365中文官方网站
2012年度,三育人积极分子,bat365中文官方网站
2011年度,先进工作者,bat365中文官方网站bat365官网登录入口
2010年度,十佳青年教工,bat365中文官方网站
代表性论文:
Q.Lei, Y. Li, H. Hou, etal. Antibody dynamics to SARS-CoV-2 in asymptomatic COVID-19 infections. Allergy. 2021;76:551–561.(通讯作者)
Y.Li,M. Ma,Q.Lei, etal. Linear epitope landscape of SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients. Cell reports, 2021,34(13): 108915. (共通讯作者)
Y.Li, D. Lai, Q. Lei, etal. Systematic evaluation of SARS-CoV-2 spike protein derived peptides for diagnosis of COVID-19 patients. Cellular and Molecular Immunology, 2021,18:621-631.(共通讯作者)
L. Hao,J. Ma,C. Shi, etal. Enhanced tuberculosis clearance through the combination treatment with recombinant adenovirus-mediated granulysin delivery.Theranostics, 2020, 10(22):10046-10056.(通讯作者)
L.Hao, Y. Wu,Y. Zhang, etal. Combinational PRR Agonists in Liposomal Adjuvant Enhances Immunogenicity and Protective Efficacy in a Tuberculosis Subunit Vaccine. Frontiers in Immunology, 2020, 11:575504. (通讯作者)
Y.Wu, M. Cai, J. Ma, etal. Heterologous Boost Following Mycobacterium bovis BCG Reduces the Late Persistent, Rather Than the Early Stage of Intranasal Tuberculosis Challenge Infection. Frontiers in Immunology, 2018, 9:2439.(通讯作者)
M. Tian, Z. Zhou, S. Tan, etal. Formulation in DDA-MPLA-TDB Liposome Enhances the Immunogenicity and Protective Efficacy of a DNA Vaccine against Mycobacterium tuberculosis Infection. Frontiers in Immunology, 2018, 9:310. (通讯作者)
J. Ma,X. Teng,X. Wang, etal. A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation. EBioMedicine, 2017, 22:143-154.(通讯作者)
Q. Yu, X. Wang, X. Fan. Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL -2+ T Cells. Frontiers in Immunology, 2017, 8:585.(通讯作者)